Which BaseSpace apps and features use Illumina Connected Analytics

Illumina Connected Analytics (ICA) is a cloud-based software platform intended to be used to manage, analyze, and interpret large volumes of multi-omics data in a secure, scalable, and flexible environment. With BaseSpace utilizing underlying features on ICA, it allows BaseSpace users to take advantage of the features and technology on the ICA platform.

BaseSpace Apps

The following BaseSpace Apps currently perform analysis on ICA:

• BCL Convert 2.5.0 and higher

• DRAGEN Enrichment 4.4.4 and higher

• DRAGEN Methylation Pipeline 4.4.4 and higher

• DRAGEN Single Cell RNA 4.4.2 and higher

• DRAGEN Germline 4.3.6 and higher

• DRAGEN Pangenome Reference Builder 4.3.6 - All Versions

• DRAGEN Reference Builder 4.3.6 and higher

• DRAGEN Baseline Builder 4.3.6 and higher

• DRAGEN Small Whole Genome Sequencing - All Versions

• DRAGEN ICLR WGS (Illumina Complete Long Reads) - All Versions

• DRAGEN Microbial Enrichment Plus - All Versions

• DRAGEN ICLR Enrichment - All Versions

• DRAGEN ILMN cfDNA Prep with Enrichment - All Versions

• DRAGEN Imputation 4.2.7

• Reference Builder (Instruments) 1.1.0 and higher

Sequencing Runs

The following sequencing runs will utilize ICA, but all files and features are accessible through BaseSpace.

• The NovaSeq X/X Plus will connect through BaseSpace and ultimately store the run files on ICA. During login, the NovaSeq X Control software will verify that all BaseSpace and ICA resources are available to make sure no issues occur during run upload.

• The NextSeq 1000/2000 will upload sequencing run files directly to BaseSpace. Starting with BCL Convert or DRAGEN 4.2.7 Planned Run Analysis, the FASTQ files and all other downstream analysis files will be stored on ICA.

BaseSpace Resources

When uploading resources through the Resources Tab, the files will be uploaded to ICA so they are accessible for any DRAGEN analysis that is autolaunched. This includes BED files or custom references hashtables.

BaseSpace Transfers

Any runs or projects containing data in ICA may take up to 24 hours to complete transfer. When the transfer is accepted, the items will be immediately visible in the recipients account, but downloading the data or using it as input will be restricted until transfer process has completed.

Data Archive

Archiving any data that is based in ICA cannot currently be archived on BaseSpace. This feature will be enabled in a future version of BaseSpace.

For any feedback or questions regarding this article (Illumina Knowledge Article #9045), contact Illumina Technical Support [email protected].