# Instrument, flow cell, and reagent requirement FAQ for Illumina DNA PCR Free libraries **Can Illumina DNA PCR-Free Tagmentation libraries be sequenced on all Illumina platforms?**\ This library type is not supported on HiSeq X, but can be sequenced on all other platforms. See the [Custom Primer Requirements for the Illumina DNA PCR-Free Prep, Tagmentation Kit article](https://knowledge.illumina.com/library-preparation/dna-library-prep/library-preparation-dna-library-prep-reference_material-list/000003343) and app note [Optimal loading concentration for Illumina DNA PCR-Free libraries](https://www.illumina.com/content/dam/illumina/gcs/assembled-assets/marketing-literature/illumina-dna-pcr-free-loading-concentration-tech-note-770-2020-007/illumina-dna-pcr-free-loading-concentration-tech-note-770-2020-007.pdf) for more details. **Which NovaSeq 6000 flow cells can be used with these libraries?**\ All NovaSeq flow cells can be used: SP, S1, S2 and S4. **If Illumina DNA PCR-Free libraries are sequenced without adding any custom primers, can the flow cell be recovered?** No. \ \ \
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