# Is the Nextera TDE1 enzyme pre loaded with oligos? The Illumina transposase enzymes function by inserting a piece of DNA at the site that is cleaved/fragmented by the enzyme in a process called tagmentation. The transposase enzyme in complex with the piece of DNA that will be inserted is referred to as a 'transposome'. **All Illumina tagmentation-based library prep kits** (including Illumina Tagment DNA TDE1 Enzyme and Buffer Kits) **come with transposase that is pre-loaded with partial adapter sequences.** The sequences of the pre-loaded adapters are provided in the [Illumina Adapter Sequences Document](https://support.illumina.com/downloads/illumina-adapter-sequences-document-1000000002694.html) in the 'Nextera Transposase Adapters' section: ![](https://761066130-files.gitbook.io/~/files/v0/b/gitbook-x-prod.appspot.com/o/spaces%2FGM9W2DuBTgEXv1ClCm8H%2Fuploads%2Fgit-blob-54b617281826cb766b21b6b9606bbd72808a3496%2Fimage1.png?alt=media) \ \ \
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