# Can Illumina RNA Prep with Enrichment library prep and enrichment reagents be purchased separately?

Library prep and enrichment reagents **can** be ordered bundled or as separate reagents\*\*\*\*\*. This supports processing samples at different plexities than recommended by Illumina.

**Bundled library prep and enrichment reagents**

* 20040536 Illumina RNA Prep with Enrichment, (L) Tagmentation (16 Samples)
  * Supports 1-plex enrichments (16 enrichments)
* 20040537 Illumina RNA Prep with Enrichment, (L) Tagmentation (96 Samples)
  * Support 3-plex enrichments (32 enrichments)

**Individual library prep reagents (pre-enrichment)**

* 20040542 Illumina RNA Prep, (L) Tagmentation (16 Samples)

**Individual enrichment reagents**

* 20040540 Illumina RNA Fast Hyb Enrichment (16 Samples)

**Note:** Indexes are not included and must be purchased separately\*\*\*\*\*.

* Recommended indexes:
  * 20091654 Illumina DNA/RNA UD Indexes Set A, Tagmentation (96 Indexes, 96 Samples)
  * 20091656 Illumina DNA/RNA UD Indexes Set B, Tagmentation (96 Indexes, 96 Samples)
  * 20091658 Illumina DNA/RNA UD Indexes Set C, Tagmentation (96 Indexes, 96 Samples)
  * 20091660 Illumina DNA/RNA UD Indexes Set D, Tagmentation (96 Indexes, 96 Samples)
* Additional indexes (Orders accepted until January 29, 2025 or until inventory is depleted):
  * 20027213 IDT for Illumina DNA/RNA UD Indexes Set A, Tagmentation (96 Indexes, 96 Samples)
  * 20027214 IDT for Illumina DNA/RNA UD Indexes Set B, Tagmentation (96 Indexes, 96 Samples)
  * 20042666 IDT for Illumina DNA/RNA UD Indexes Set C, Tagmentation (96 Indexes, 96 Samples)
  * 20042667 IDT for Illumina DNA/RNA UD Indexes Set D, Tagmentation (96 Indexes, 96 Samples)

**Note:** The Illumina Exome Panel and Respiratory Virus Oligo Panel v2 (RVOP v2) enrichment oligo panels are not included and must be purchased separately.

**\***The [Respiratory Pathogen ID/AMR (RPIP) Enrichment Panel](https://www.illumina.com/products/by-type/sequencing-kits/library-prep-kits/respiratory-pathogen-id-panel.html) is configured as a bundled kit. The kit contains library prep reagents to prepare 96 samples with 32 3-plex enrichments, indexes (Set A or Set B), enrichment oligo panel, and analysis with the IDbyDNA RPIP Explify app. The last order date for kits that ship with IDT for Illumina DNA/RNA UD Indexes will be January 30, 2025, with last ship date of March 30, 2025 per PCN2024-1649. After these dates, kits will ship with Illumina DNA/RNA UD Indexes instead.

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| *For any feedback or questions regarding this article (Illumina Knowledge Article #6623), contact Illumina Technical Support* [*techsupport@illumina.com*](mailto:techsupport@illumina.com?subject=Question%2FFeedback%20Regarding%20Illumina%20Knowledge%20Article%20#000006623%20-%20Library%20Preparation%20\&body=Dear%20Illumina%20Technical%20Support,%0D%0A%0D%0A)*.* |


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