> For the complete documentation index, see [llms.txt](https://knowledge.illumina.com/llms.txt). Markdown versions of documentation pages are available by appending `.md` to page URLs; this page is available as [Markdown](https://knowledge.illumina.com/instrumentation/iseq-100/instrumentation-iseq-100-reference_material-list/000002289.md).
# Power cycling the iSeq 100
1. From the control software menu, select **Shut Down System**.
1. If the system does not shut down, hold the power button on the left side of the instrument until the lights fade.
2. When the power button pulses, toggle the power switch on the back of the instrument to the OFF position.
3. Wait a minimum of 30 seconds.
4. Toggle the power switch back to the ON position.
5. Press the power button on the left side once it begins pulsing with light.
6. The control software will launch automatically once the boot completes and the local user account is logged into (eg, sbsuser).
\
\
\
| |
| :--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------: |
| *For any feedback or questions regarding this article (Illumina Knowledge Article #2289), contact Illumina Technical Support* [*techsupport@illumina.com*](mailto:techsupport@illumina.com?subject=Question%2FFeedback%20Regarding%20Illumina%20Knowledge%20Article%20#000002289%20-%20Instrumentation%20\&body=Dear%20Illumina%20Technical%20Support,%0D%0A%0D%0A)*.* |
---
# Agent Instructions
This documentation is published with GitBook. GitBook is the documentation platform designed so that both humans and AI agents can read, navigate, and reason over technical content effectively. Learn more at gitbook.com.
## Querying This Documentation
If you need additional information that is not directly available in this page, you can query the documentation dynamically by asking a question.
Perform an HTTP GET request on the current page URL with the `ask` query parameter:
```
GET https://knowledge.illumina.com/instrumentation/iseq-100/instrumentation-iseq-100-reference_material-list/000002289.md?ask=
```
The question should be specific, self-contained, and written in natural language.
The response will contain a direct answer to the question and relevant excerpts and sources from the documentation.
Use this mechanism when the answer is not explicitly present in the current page, you need clarification or additional context, or you want to retrieve related documentation sections.