# Mitigating Instrument Platform Services Errors on the MiSeq i100 Series **Background** The Control Software on the MiSeq i100 Series establishes a connection between the user-facing control computer and the internal compute engine that manages data processing. If this connection is not established successfully, the Control Software presents the following error: ![](https://761066130-files.gitbook.io/~/files/v0/b/gitbook-x-prod.appspot.com/o/spaces%2FGM9W2DuBTgEXv1ClCm8H%2Fuploads%2Fgit-blob-0a29862a6ba3b8fea19db8bd77c325c3a37f1767%2Fimage1.png?alt=media) There was a problem with instrument platform services. You can try to restart the control software, or shutdown and restart the instrument. If this issue presents, select **Restart Application** to restart the Control Software and allow the Software to re-establish the connection between the two computers. Do **NOT** select Shut down as this can frequently result in the issue persisting. If the issue persists after selecting **Restart Application**, contact [Illumina Tech Support](https://www.illumina.com/company/contact-us.html). \ \ \
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