# Troubleshooting access to the path Global\Local Run Manager is denied on MiSeq
Users may encounter the error "Access to the path 'Global\Local Run Manager' is denied." while attempting to close or re-initialize the MiSeq Control Software.
This error may be the result of failing to power cycle the instrument after updating the log-on credentials on the instrument.
To resolve this error:
1. Power Cycle the instrument. Instructions for this may be found in the Illumina Knowledge article [How to shut down or power cycle the MiSeq](https://knowledge.illumina.com/instrumentation/miseq/instrumentation-miseq-reference_material-list/000001894/?utm_source=agent\&utm_medium=email\&utm_campaign=kb)
2. Ensure all log-on credentials are configured as recommended in the Illumina Knowledge article [How to connect benchtop instruments and Local Run Manager to a network location](https://knowledge.illumina.com/instrumentation/general/instrumentation-general-reference_material-list/000001934).
If the error persists, contact [Illumina Technical Support](https://www.illumina.com/company/contact-us.html#/united-states/technical-support).
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| *For any feedback or questions regarding this article (Illumina Knowledge Article #8538), contact Illumina Technical Support* [*techsupport@illumina.com*](mailto:techsupport@illumina.com?subject=Question%2FFeedback%20Regarding%20Illumina%20Knowledge%20Article%20#000008538%20-%20Instrumentation%20\&body=Dear%20Illumina%20Technical%20Support,%0D%0A%0D%0A)*.* |
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