# Troubleshooting a Flow Cell Registration Failed (Skew) warning on the NextSeq 500/550 The following error message can occur during pre-run checks and is caused by a software communication issue and generally does not impact run performance. The error states "Flow Cell Registration Failed (skew). No action necessary", as shown below. ![](https://761066130-files.gitbook.io/~/files/v0/b/gitbook-x-prod.appspot.com/o/spaces%2FGM9W2DuBTgEXv1ClCm8H%2Fuploads%2Fgit-blob-3599b8909df464dc4a892710d1755aa498ce6b23%2Fimage1.jpg?alt=media\&token=12154609-619b-4404-ac7d-b47ff8b5fa21) **Troubleshooting steps:** * Monitor run until completion and review run specifications. * If run does not meet specifications, contact [Illumina Technical Support](https://www.illumina.com/company/contact-us.html#/united-states/technical-support). * Power cycle instrument before next run. For further information, search for Knowledge Base articles **Specifications for the NextSeq 500/550** and **How to Perform a NextSeq 500/550 Power Cycle.** \ \ \
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