> For the complete documentation index, see [llms.txt](https://knowledge.illumina.com/llms.txt). Markdown versions of documentation pages are available by appending `.md` to page URLs; this page is available as [Markdown](https://knowledge.illumina.com/instrumentation/miniseq/instrumentation-miniseq-troubleshooting-list/000001815.md).

# Troubleshooting "Y Stage Initialization Error Operation home failed..." errors on the MiniSeq

The MiniSeq Control Software (MnCS) may fail to initialize and display the following error message:

*(33) Operation home failed due to flowcell\_y not being able to move to flowcell\_y\_home =1" and "(66) flowcell\_y stopped due to safety\_interlock"*

This error may result from a communication issue on the MiniSeq.

**Troubleshooting steps:**

1. Power cycle the MiniSeq following the instructions in [How to Power Cycle the MiniSeq](/instrumentation/miniseq/instrumentation-miniseq-reference_material-list/000002010.md). Perform the power cycle according to the Control Software version installed in your MiniSeq.
2. After the Power cycle, restart the MnCS. If the MnCS initiliazes without issues, proceed with your workflow.
3. If the error replicates after the power cycle, contact [Illumina Technical Support](https://www.illumina.com/company/contact-us.html#/united-states/technical-support) for the next steps.

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| *For any feedback or questions regarding this article (Illumina Knowledge Article #1815), contact Illumina Technical Support* [*techsupport@illumina.com*](mailto:techsupport@illumina.com?subject=Question%2FFeedback%20Regarding%20Illumina%20Knowledge%20Article%20#000001815%20-%20Instrumentation%20\&body=Dear%20Illumina%20Technical%20Support,%0D%0A%0D%0A)*.* |


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