# How to use the Illumina Sequencing Coverage Calculator Video

In this video, we will walk through using the Illumina Sequencing Coverage Calculator to determine the number of samples per MiniSeq or NovaSeq 6000 run. We'll go through specific examples for whole-genome sequencing (WGS), custom DNA content, total RNA-Seq, and a pre-defined panel: the AmpliSeq for Illumina Focus panel.

To access the Illumina Sequencing Coverage Calculator, visit [here](https://support.illumina.com/downloads/sequencing_coverage_calculator.html).

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{% embed url="<https://www.youtube.com/watch?v=UBy1P327-9Q&ab_channel=Illumina>" %}

Video length: 4:47 min

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| *For any feedback or questions regarding this article (Illumina Knowledge Article #5861), contact Illumina Technical Support* [*techsupport@illumina.com*](mailto:techsupport@illumina.com?subject=Question%2FFeedback%20Regarding%20Illumina%20Knowledge%20Article%20#000005861%20-%20Library%20Preparation%20\&body=Dear%20Illumina%20Technical%20Support,%0D%0A%0D%0A)*.* |


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