Software update best practices on the iSeq 100

General Notes

Updating the software ensures that the system has the latest features and fixes. Software updates are bundled into a system suite, which includes the following software.

• iSeq 100 Control Software

• iSeq 100 sequencing recipes

• Universal Copy Service

• Real-Time Analysis

• Local Run Manager (framework only)

  • Although Local Run Manager is included in the system suite, the analysis modules are not. Install them separately as needed, using the sbsadmin account. Access the analysis module software from the Local Run Manager support page.

The system is configured to download software updates automatically or manually.

• Automatic updates: Updates are automatically downloaded from BaseSpace Sequence Hub to the instrument to install. This option requires an internet connection, but does not require a BaseSpace Sequence Hub account.

• Manual updates: Updates are manually downloaded from the web, saved locally or to a portable device, and installed from the saved location. This option does not require an internet connection.

Install an Automatic Software Update

1. Switch to the sbsadmin operating system account.

2. Select the control software menu, and then select Software Update to open the Software Update dialog box.

   1. Systems configured for automatic updates display an alert when a software update is available.

3. To check for an update, select one of the following options.

   1. Check for Update: Check for a software update.

   2. Autocheck for Updates: Check for a software update and configure the system to automatically check for future updates.

4. Select Update to download the new version of software.

   1. When the download is complete, the control software closes and the installation wizard appears.

   2. The control software automatically restarts. Any firmware update occurs automatically after the restart.

   3. Canceling an update is not possible after installation begins. It is only possible to cancel an update during the download step.

Install a Manual Software Update

1. Switch to the sbsadmin operating system account.

2. When a software update is available, download the suite installer (\*.exe) from the iSeq 100 Sequencing System support page. Save the installer to a local or portable drive.

3. If the installer is saved to a portable drive, plug the drive into a USB port on the back of the instrument. Move the instrument as needed to access the back.

4. From the control software, select Software Update from the control software menu.

5. In the Software Update dialog box, expand Install from local or portable drive.

6. Select Browse to navigate to the installer.

7. Select Update to start installation.

   1. The control software closes and the installation wizard appears.

   2. The control software automatically restarts. Any firmware update occurs automatically after the restart.

   3. Canceling an update is not possible after installation begins. It is only possible to cancel an update during the download step.

For any feedback or questions regarding this article (Illumina Knowledge Article #6675), contact Illumina Technical Support [e-mail].