> For the complete documentation index, see [llms.txt](https://knowledge.illumina.com/llms.txt). Markdown versions of documentation pages are available by appending `.md` to page URLs; this page is available as [Markdown](https://knowledge.illumina.com/instrumentation/nextseq-1000-2000/instrumentation-nextseq-1000-2000-reference_material-list/000003039.md).

# Purge settings on the NextSeq 1000/2000

Users can choose to purge reagents from the cartridge once a run completes. Purging reagents will move the remaining contents from the reagent cartridge to the spent reagents compartment.

1. From the control software menu, select **Settings**.
2. Choose whether the system automatically purges unused reagents to the spent reagents compartment after each run to streamline waste disposal after run completion:

* To purge automatically, select the **Purge Reagent Cartridge** checkbox\*.
* To skip automatic purging, deselect the **Purge Reagent Cartridge** checkbox (this is the default setting). ![](/files/8xMs1xcFjQW9j1hu6lF4)

3. Select **Save**.

**\***&#x50;urging unused reagents adds up to 2 hours to the workflow.\
\
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| *For any feedback or questions regarding this article (Illumina Knowledge Article #3039), contact Illumina Technical Support* [*techsupport@illumina.com*](mailto:techsupport@illumina.com?subject=Question%2FFeedback%20Regarding%20Illumina%20Knowledge%20Article%20#000003039%20-%20Instrumentation%20\&body=Dear%20Illumina%20Technical%20Support,%0D%0A%0D%0A)*.* |


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