# How to Disable Cloud Login Feature on the MiSeq i100 and NovaSeq X Series

**Background**

The MiSeq i100 and NovaSeq X Series instruments require users login to the Control Software using either a Local or Cloud login. If the instrument is not connected to the internet and the Cloud login is not required, use the following steps to disable the Cloud login feature and only use the Local login.

The Cloud login should only be disabled if the instrument is completely disconnected from an internet connection. This procedure disables all Cloud upload features including both Proactive and BaseSpace features. For more information on Proactive, see the following resources:

[Illumina Proactive - Instrument Services](https://www.illumina.com/services/instrument-services/instrument-monitoring.html)

[Proactive connectivity guide for Miseqâ„¢ i100 Series](https://www.illumina.com/content/dam/illumina/gcs/assembled-assets/marketing-literature/proactive-connect-guide-miseqi100-m-gl-03317/proactive-connect-guide-miseqi100-m-gl-03317.pdf)

[Proactive connectivity guide for NovaSeq X Series](https://www.illumina.com/content/dam/illumina/gcs/assembled-assets/marketing-literature/proactive-connect-guide-novaseqx-m-gl-03319/proactive-connect-guide-novaseqx-m-gl-03319.pdf)

**Resolution Actions**

*Disabling Cloud Login*

1. Ensure the instrument is idle and there are no Active sequencing Runs or DRAGEN Analyses.
2. Log into the instrument as an **Administrator** account.
3. Access the **Settings Menu**:
   1. On the *MiSeq i100 Series* Control Software Home screen, select the **dropdown menu** in the top-left corner, then select **Settings**.
   2. On the *NovaSeq X Series* Control Software Home screen, select the **instrument icon,** then select **Settings**.
4. Select **Cloud Settings**.
5. De-select all checkboxes under **Run settings** and **Illumina Proactive**.
6. Remove any entries in the **Private domain name** field.
7. Within the **Hosting Location** dropdown menu, select the **blank entry** above the BSSH USA (N. Virginia) selection (**Figure 1**).
   1. The Hosting location selection should be empty after selection (**Figure 2**).
8. Select **Save**.

If the Cloud Settings menu presents the message "An unexpected error has occurred. Details: Internal Server Error," see the following steps.

1. Navigate to the **Cloud Settings** menu.
2. Confirm that all checkboxes are de-selected and the Hosting Location is blank.
3. Select **Save**, then wait 2 minutes. It is expected to display a 'loading circle' that does not resolve.
4. After 2 minutes, select the **X** in the top-right corner of the Cloud Settings UI.
5. Navigate back to the **Home** screen, then select the **dropdown menu** in the top-left corner, and then **sign out** of the Admin account.
6. Click the screen to initiate Control Software login and confirm if Local Login presents as the default option.

![](/files/fxcq3tRYKOMwqJUkD5yB)

**Figure 1**: Highlighting the empty Hosting location selection within the dropdown menu.

![](/files/AdPntF3FoBXQjOXJ3qBJ)

**Figure 2**: Highlighting the empty Hosting location selection.

*Re-enabling Cloud Login*

1. Ensure the instrument is idle and there are no Active sequencing Runs or DRAGEN Analyses.
2. Login to the instrument as an **Administrator** account.
3. Access the **Settings Menu**:
   1. On the *MiSeq i100 Series* Control Software Home screen, select the **dropdown menu** in the top-left corner, then select **Settings**.
   2. On the *NovaSeq X Series* Control Software Home screen, select the **instrument icon,** then select **Settings**.
4. Select **Cloud Settings**.
5. Select the appropriate regional **Hosting Location** using the dropdown menu.
6. For Enterprise users, input the **Private domain name** in the free text field.
7. Select the desired checkboxes under **Run settings** and **Illumina Proactive**.
   1. Illumina Proactive - Uploads hardware and run performance data to Illumina Support for troubleshooting purposes.
   2. Cloud run monitoring - Uploads run metrics to BaseSpace for user run monitoring.
   3. Cloud run storage - Uploads run metrics and data to BaseSpace, required for Cloud Analysis.
8. Select **Test Configuration** and confirm all required URLs are reachable.
   1. Consult the local IT team to add the affected URLs to local network security allow list if any URLs are not reachable.
9. If **Test Configuration** is PASS, select **Save**.

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| *For any feedback or questions regarding this article (Illumina Knowledge Article #9462), contact Illumina Technical Support* [*techsupport@illumina.com*](mailto:techsupport@illumina.com?subject=Question%2FFeedback%20Regarding%20Illumina%20Knowledge%20Article%20#000009462%20-%20Instrumentation%20\&body=Dear%20Illumina%20Technical%20Support,%0D%0A%0D%0A)*.* |


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