Computer Hardware Specifications for NovaSeq 6000
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The NovaSeq 6000 includes two computer systems, the Compute Engine (CE) and the Control Computer (SBC). The SBC is a Windows-based computer mapped to the C and D drive, whereas the CE is a Linux-based computer mapped to the Z:\ drive and stores .cbcl data before copying to the network drive.
Specifications for each drive on NovaSeq6000:
Single-Board Computer (SBC): total available space is 250 GB (partitioned into C:\ and D:\ drives).
C drive - 174 GB available
Windows 10 Version: Windows 10 Enterprise LTSC.
Contains Windows and Maintenance Logs.
Contains information from NovaSeq Control Software (NVCS), NovaSeq Service Software (NVSS), and Universal Copy Service (UCS).
Responsible for USB and Ethernet port management.
Requires the following amount of space to start a run: - SP run: 5 GB - S1 run: 20 GB - S2 run: 20 GB - S4 run: 40 GB
D drive - 64 GB
Stores instrument performance data.
The instrument will manage the data on this drive automatically in most cases.
Compute Engine (CE) drive (Linux): Early models have 2.85 TB; Current production models have 3.14 TB of space available.
Runs Real Time Analysis v3 (RTA3) and handles data processing.
Will be mapped as the Z:\ drive.
Has a single folder, 'outputfolder' that will have the run data.
Requires the following amount of space per cycle to start run:
S1 run: 1.35 GB
S2 run: 5.4 GB
S4 run: 4.3 GB
Runs must be backed up to a network location (either local network or BaseSpace Sequence Hub).
Disc space is checked at the start of each run (clear space using Process Management only).
Requires 1 GB ethernet connection.
Recommended using CAT-6 shielded cable.
200 MB/s upload speed for Base Space Sequence Hub (BSSH) (5 MB/s for Proactive data).
Dedicated internal IP connections. For more information, refer to NovaSeq 6000 .
A network card capable of up to 1 Gbps speed is required.
Information about the power cord:
NovaSeq 6000 instrument ships with UPS ().
User socket to the uninterruptible power supply (UPS) uses power cord: NEMA-L6-20P to C19 This is a US/ Canada/ South America (not Brazil) cord & is 8 ft (2.5 m) long.
Other regions have different cords, but all are typically 2.5 meters long.
UPS backup outlet to NovaSeq 6000 uses power cord: C20 to C19. This is used on almost all UPS (not Japan) and is 2 meters (6 ft) long.
UPS cord connects to electrical supply with locking connection plug (type L6-20P), which needs an L6-20R socket.
The NovaSeq 6000 computer name can be changed with the following steps.
File Explorer, right-click on "This PC" and select Properties.
In properties, select "Change settings" for the computer name, domain, and workgroup settings.
For any feedback or questions regarding this article (Illumina Knowledge Article #2428), contact Illumina Technical Support .