> For the complete documentation index, see [llms.txt](https://knowledge.illumina.com/llms.txt). Markdown versions of documentation pages are available by appending `.md` to page URLs; this page is available as [Markdown](https://knowledge.illumina.com/instrumentation/nextseq-1000-2000/instrumentation-nextseq-1000-2000-troubleshooting-list/000007809.md).

# Troubleshooting "Failed to send WATCHDOG=1 notification message:" on the NextSeq 1000/2000

NextSeq 1000/2000 users may see the following error appear on a black screen.

"Failed to send WATCHDOG=1 notification message: Transport endpoint is not connected"

![](/files/coGEHS58POxg6bQEWjuP)

This message is typically indicative that there are files being transferred while a user is attempting to perform another process that would affect that transfer. This can be resolved with a slow power cycle of the instrument.

**How to Power Cycle the NextSeq 1000/2000**

1. In the control software, open the hamburger menu (three horizontal lines) and select **Shutdown Instrument**.
2. Once the instrument is off, toggle the power switch to the **OFF** position.
3. Wait a minimum of 5 minutes with the instrument powered completely off.
4. Toggle the power switch to the **ON** position.
5. Once the power button on the front right of the instrument is pulsing with light, press it.
6. If this does not resolve the error, contact Illumina Technical Support at <techsupport@illumina.com>

\
\
\ <br>

|                                                                                                                                                                                                                                                                                                                                                                        |
| :--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------: |
| *For any feedback or questions regarding this article (Illumina Knowledge Article #7809), contact Illumina Technical Support* [*techsupport@illumina.com*](mailto:techsupport@illumina.com?subject=Question%2FFeedback%20Regarding%20Illumina%20Knowledge%20Article%20#000007809%20-%20Instrumentation%20\&body=Dear%20Illumina%20Technical%20Support,%0D%0A%0D%0A)*.* |


---

# Agent Instructions
This documentation is published with GitBook. GitBook is the documentation platform designed so that both humans and AI agents can read, navigate, and reason over technical content effectively. Learn more at gitbook.com.

## Querying This Documentation
If you need additional information that is not directly available in this page, you can query the documentation dynamically by asking a question.

Perform an HTTP GET request on the current page URL with the `ask` query parameter:

```
GET https://knowledge.illumina.com/instrumentation/nextseq-1000-2000/instrumentation-nextseq-1000-2000-troubleshooting-list/000007809.md?ask=<question>
```

The question should be specific, self-contained, and written in natural language.
The response will contain a direct answer to the question and relevant excerpts and sources from the documentation.

Use this mechanism when the answer is not explicitly present in the current page, you need clarification or additional context, or you want to retrieve related documentation sections.