What GTC files can be used with DRAGEN Array Local?

DRAGEN Array Local can be used to generate Genotype Call (GTC) files, which are then used to generate SNV VCF and CNV VCF files.

• The 'genotype call' command is used to call genotypes and generate GTC files

• The 'genotype gtc-to-vcf' command is used to generate SNV VCF files

• The 'copy-number call' command is used to generate CNV VCF files

The DRAGEN Array 'genotype gtc-to-vcf' or 'copy-number call' commands are only applicable for GTC files produced by DRAGEN Array using the 'genotype call' command.

GTC files generated from the scanning instrument or using software (eg, Beeline Autoconvert or LIMS AutoCall) cannot be used with the DRAGEN Array 'genotype gtc-to-vcf' or 'copy-number call' commands.

For more information, see the DRAGEN Array User Guide.

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