Air filter replacement on the NextSeq 1000/2000

The air filter is a single-use rectangular cartridge that covers the fan on the right side of the NextSeq 1000/2000 instruments. It allows for proper cooling and prevents debris from entering the system. The instrument ships with one air filter installed and one spare. Additional air filters are included with an active instrument service contract (filters are not sent automatically; rather, users can request them by send an email to Illumina Technical Support, [e-mail]), or they can be purchased separately from Illumina.

NextSeq 1000/2000 air filter catalog numbers:

• NextSeq 1000/2000 Air Filter Quantity 1: 20029759

• NextSeq 1000/2000 Air Filter Quantity 2: 20041831

Use the following instructions to replace an expired air filter every 6 months.

Replacing the Air Filter

1. On the top of the instrument, press the right side of the top panel to disengage, as shown in the following illustration.

2. Open the panel.

3. Press to release the air filter cartridge, remove it from the center of the panel, and discard it.

4. Insert a new air filter into the receptacle, and press to secure.

5. Close the top panel and press it into place.

See also the maintenance Section of the NextSeq 1000 and 2000 Sequencing System Guide.

This information is also available in video form. Search for Knowledge Base article How To Replace the NextSeq 1000/2000 Air Filter Video.

For any feedback or questions regarding this article (Illumina Knowledge Article #5457), contact Illumina Technical Support [e-mail].