Are tip guides required for Tecan/IAPS with ILASS?

The Tecan/Infinium Automated Pipetting System (IAPS) with Illumina Automation Control (IAC) software is used to perform automated Infinium workflow for legacy Infinium BeadChip formats such as Infinium HD, HTS, LCG, and XT. The Tecan/IAPS with IAC uses Illumina Teflon tips and requires tip guides that are placed on top of the BeadChip to dispense samples properly during the Hybridization step.

The Tecan/Infinium Automated Pipetting System (IAPS) with Illumina Lab Automation Software Solution (ILASS) is used to perform automated Infinium workflow for Infinium EX Genotyping and EX Methylation formats and select legacy Infinium formats (HD Methylation). The Tecan/IAPS with ILASS uses Tecan fixed tips and does not use tip guides for BeadChip sample hybridization.

Instrument and software	Compatible BeadChip formats	LiHa Tip type	Tip guide
Tecan/IAPS with IAC	HD (Ultra, Super, Methylation), HTS, LCG (8-sample, Quad), XT	Illumina Teflon tips	Required
Tecan/IAPS with ILASS	EX (Genotyping, Methylation), HD Methylation	Tecan fixed tips	Not used

For additional information, see the following:

• Infinium LiHa and Infinium RoMA Operating Manual

• Infinium RoMA (IAPS with ILASS) Product Documentation

• Illumina Automation Control Release Notes

• ILASS Infinium Module Release Notes

For any feedback or questions regarding this article (Illumina Knowledge Article #9625), contact Illumina Technical Support [e-mail].