How to Power Cycle the NovaSeq 6000 System

Illumina recommends power cycling, if needed, during troubleshooting. Regular weekly power cycles are not required on the NovaSeq 6000.

To power cycle the NovaSeq 6000, use the following steps. * Choose Instrument Shut Down from the NovaSeq Control Software (NVCS) dropdown menu.

• When the monitor shuts down, use the toggle switch at the rear right of the instrument to switch the instrument OFF.

• Wait 1-2 minutes.

• Use the toggle switch to turn the instrument ON.

• Wait for the power button to start to pulse.; this can take a few seconds.

• Use the power button on the right front side of the instrument to turn the instrument computer ON.

• Log in to Windows

• Wait for Windows to load, then select the NovaSeq Control Software icon to initialize the instrument.

For further information, search for Knowledge Base article How To Power Cycle The NovaSeq 6000 Video.

For any feedback or questions regarding this article (Illumina Knowledge Article #2470), contact Illumina Technical Support [e-mail].