# Troubleshooting

Software > General > Troubleshooting

* [DRAGEN reference differences for on instrument and standalone analysis](https://knowledge.illumina.com/software/general/software-general-troubleshooting-list/000009589)
* [Does the DRAGEN pipeline support VQSR (Variant Quality Score Recalibration)?](https://knowledge.illumina.com/software/general/software-general-troubleshooting-list/000006139)
* [How to troubleshoot a "None of the specified endpoints were reachable" error in Local Run Manager](https://knowledge.illumina.com/software/general/software-general-troubleshooting-list/000001217)
* [Illumina Connected Analytics (ICA) kernel cannot connect in a Bench Workspaces](https://knowledge.illumina.com/software/general/software-general-troubleshooting-list/000007769)
* [Options for demultiplexing libraries with different index lengths in the same sequencing run](https://knowledge.illumina.com/software/general/software-general-troubleshooting-list/000005982)
* [Sample specific nucleotide error bias estimation filter and systematic noise filter in DRAGEN](https://knowledge.illumina.com/software/general/software-general-troubleshooting-list/000006989)
* [Troubleshooting LRM analysis module not available at run start on NextSeq 500/550](https://knowledge.illumina.com/software/general/software-general-troubleshooting-list/000001904)