# Troubleshooting

Software > General > Troubleshooting

* [DRAGEN reference differences for on instrument and standalone analysis](/software/general/software-general-troubleshooting-list/000009589.md)
* [Does the DRAGEN pipeline support VQSR (Variant Quality Score Recalibration)?](/software/general/software-general-troubleshooting-list/000006139.md)
* [How to troubleshoot a "None of the specified endpoints were reachable" error in Local Run Manager](/software/general/software-general-troubleshooting-list/000001217.md)
* [Illumina Connected Analytics (ICA) kernel cannot connect in a Bench Workspaces](/software/general/software-general-troubleshooting-list/000007769.md)
* [Options for demultiplexing libraries with different index lengths in the same sequencing run](/software/general/software-general-troubleshooting-list/000005982.md)
* [Sample specific nucleotide error bias estimation filter and systematic noise filter in DRAGEN](/software/general/software-general-troubleshooting-list/000006989.md)
* [Troubleshooting LRM analysis module not available at run start on NextSeq 500/550](/software/general/software-general-troubleshooting-list/000001904.md)


---

# Agent Instructions: Querying This Documentation

If you need additional information that is not directly available in this page, you can query the documentation dynamically by asking a question.

Perform an HTTP GET request on the current page URL with the `ask` query parameter:

```
GET https://knowledge.illumina.com/software/general/software-general-troubleshooting-list.md?ask=<question>
```

The question should be specific, self-contained, and written in natural language.
The response will contain a direct answer to the question and relevant excerpts and sources from the documentation.

Use this mechanism when the answer is not explicitly present in the current page, you need clarification or additional context, or you want to retrieve related documentation sections.