Windows 10 support and timelines for Illumina sequencing and array instrument computers

Microsoft has announced that standard retail versions of Windows 10 will reach End of Life (EoL) in October 2025. This does not apply to Illumina instruments.

Illumina does not support upgrading sequencing or array instruments to Windows 11. Illumina will provide more information in the future about the process to upgrade the operating system (OS) of instruments prior to any OS End of Life.

Windows 10 versions and timeline information:

• Sequencing instruments running Windows — including iSeq 100, MiSeq, MiniSeq, NextSeq 500/550, and NovaSeq 6000 — run on Microsoft Windows 10 Enterprise LTSB (build 1607) with extended support through October 13, 2026 or Microsoft Windows 10 Enterprise LSTC (build 1809), with extended support through January 09, 2029.

• Array instruments — iScan and Tecan EVO — run on Windows 10 1607 LTSB (x64), with extended support through October 13, 2026.

For more information on timelines, see the following Microsoft resources. Note: this information is not provided or curated by Illumina.

• Windows 10 2016 LTSB support/lifecycle

• Windows 10 Enterprise LTSC 2019 support/lifecycle

• Microsoft Fixed Lifecycle Policy

To identify the Windows 10 version is currently installed on an instrument, see Knowledge article Operating System (OS) versions on Illumina platforms.

For any feedback or questions regarding this article (Illumina Knowledge Article #9668), contact Illumina Technical Support [email protected].