How to troubleshoot "The instrument encountered a thermal coolant error" on the NovaSeq X/X Plus
Error message: "Critical System Error: The instrument encountered a thermal coolant error. Please shutdown the instrument and contact Illumina Technical Support".
Troubleshooting steps:
Contrary to the error statement, do not immediately power cycle the instrument.
Collect the following Logs depending on error context:
If during a sequencing run, collect the Logs.zip file from /usr/local/illumina/runs/[RunID]/Logs
If during initialization or instrument idle, collect the
novaseq-x-series-control-software
folder in the /usr/local/illumina/logs directory.
Contact Illumina Tech Support for next steps to troubleshoot this issue.
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