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How to troubleshoot ‘The instrument encountered a thermal coolant error’ on the NovaSeq X/X Plus
**Error Message**: “ Critical System Error: The instrument encountered a thermal coolant error. Please shutdown the instrument and contact Illumina Technical Support”.**
- 1.Contrary to the error statement, do not immediately power cycle the instrument.
- 2.Collect the following Logs depending on error context:
- 1.If during a sequencing run, collect the Logs.zip file from /usr/local/illumina/runs//Logs
- 2.If during initialization or instrument idle, collect the novaseq-x-series-control-software folder in the /usr/local/illumina/logs directory.