# Instrument compatibility for sequencing TruSight Oncology 500 (TSO500) ctDNA libraries

TruSight Oncology 500 (TSO500) ctDNA libraries are compatible with the NovaSeq 6000. Illumina has not validated TSO500 ctDNA with any other sequencers. Illumina cannot guarantee performance, nor provide guidance on using other sequencers.

See the [TruSight Oncology 500 ctDNA Compatible Products support page](https://support.illumina.com/sequencing/sequencing_kits/trusight-oncology-500-ctDNA/compatibility.html) for additional compatibility information.

\
\
\ <br>

|                                                                                                                                                                                                                                                                                                                                                                              |
| :--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------: |
| *For any feedback or questions regarding this article (Illumina Knowledge Article #2922), contact Illumina Technical Support* [*techsupport@illumina.com*](mailto:techsupport@illumina.com?subject=Question%2FFeedback%20Regarding%20Illumina%20Knowledge%20Article%20#000002922%20-%20Library%20Preparation%20\&body=Dear%20Illumina%20Technical%20Support,%0D%0A%0D%0A)*.* |


---

# Agent Instructions: Querying This Documentation

If you need additional information that is not directly available in this page, you can query the documentation dynamically by asking a question.

Perform an HTTP GET request on the current page URL with the `ask` query parameter:

```
GET https://knowledge.illumina.com/library-preparation/trusight-oncology-tumor/library-preparation-trusight-oncology-tumor-reference_material-list/000002922.md?ask=<question>
```

The question should be specific, self-contained, and written in natural language.
The response will contain a direct answer to the question and relevant excerpts and sources from the documentation.

Use this mechanism when the answer is not explicitly present in the current page, you need clarification or additional context, or you want to retrieve related documentation sections.
