# How to set up a NextSeq 500/550 to upload to a BaseSpace Enterprise account using NCS v.4.0.1

NextSeq Control Software (NCS) v.4.0.1 allows for changing the Hosting Location for BaseSpace and to set a Private Domain for uploading run data using the following steps.

1. From the NCS home page, navigate to Manage Instrument.

![](https://761066130-files.gitbook.io/~/files/v0/b/gitbook-x-prod.appspot.com/o/spaces%2FGM9W2DuBTgEXv1ClCm8H%2Fuploads%2Fgit-blob-ee387c7f37a07c339029c9b4ab7f42c2f2a1a349%2Fimage1.png?alt=media)

2. Select System Configuration.

![](https://761066130-files.gitbook.io/~/files/v0/b/gitbook-x-prod.appspot.com/o/spaces%2FGM9W2DuBTgEXv1ClCm8H%2Fuploads%2Fgit-blob-25778625e2239d0ae64ab819279bfa3053ac6813%2Fimage2.png?alt=media)

3. Then, select BaseSpace Sequence Hub Configuration.

![](https://761066130-files.gitbook.io/~/files/v0/b/gitbook-x-prod.appspot.com/o/spaces%2FGM9W2DuBTgEXv1ClCm8H%2Fuploads%2Fgit-blob-4061ab2fd3383904e1758276f0e73b537b32ef74%2Fimage3.png?alt=media)

4. Change the Hosting Location to the appropriate region and check the box for Private Domain. Enter the {Domain Name}. in the text box to designate the Enterprise Account Domain. Once done, select Save.

![](https://761066130-files.gitbook.io/~/files/v0/b/gitbook-x-prod.appspot.com/o/spaces%2FGM9W2DuBTgEXv1ClCm8H%2Fuploads%2Fgit-blob-2c6bf163dfb34a98700ba4244f69d8013ef2d26c%2Fimage4.png?alt=media)

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