# How to Specify Adapters for Trimming in Local Run Manager
**How to Specify Adapters for Trimming in Local Run Manager**
1. From the Module-Specific Settings section of the Create Run screen, select "Show Advanced Settings".
2. Select "+ Add custom setting."
3. In the custom setting field, enter the setting name, in this case: "Adapter."
4. In the setting value field, enter the setting value. In order to specify 2 different adapter sequences for Read 1, type in the two sequences separated with a plus (+) sign. These will be assessed as separate adapters.\
5. If a Read 2 adapter trimming sequence is also needed, repeat steps 2 - 4, but use the setting name "AdapterRead2." In order to specify 2 different adapter sequences for Read 2, type in the two sequences separated with a plus (+) sign. These will be assessed as separate adapters. 
6. To remove a setting, select the "X".
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