# Running DRAGEN analyses with ORA files as input

DRAGEN ORA files can be used **directly** as input for the **map/align** step or they can be decompressed to **FastQ files first.** Here are a few scenarios which use ORA files as input and the flags that need to be included in said analyses.

![](https://761066130-files.gitbook.io/~/files/v0/b/gitbook-x-prod.appspot.com/o/spaces%2FGM9W2DuBTgEXv1ClCm8H%2Fuploads%2Fgit-blob-9f984fab3253edc32955e2aab3fed32761f9c52a%2Fimage1.jpg?alt=media)

More information about ORA compression/decompression can be found in the [user guide](https://support-docs.illumina.com/SW/DRAGEN_v40/Content/SW/DRAGEN/ORACompression.htm).

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