# Running DRAGEN analyses with ORA files as input
DRAGEN ORA files can be used **directly** as input for the **map/align** step or they can be decompressed to **FastQ files first.** Here are a few scenarios which use ORA files as input and the flags that need to be included in said analyses.
More information about ORA compression/decompression can be found in the [user guide](https://support-docs.illumina.com/SW/DRAGEN_v40/Content/SW/DRAGEN/ORACompression.htm).
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