> For the complete documentation index, see [llms.txt](https://knowledge.illumina.com/llms.txt). Markdown versions of documentation pages are available by appending `.md` to page URLs; this page is available as [Markdown](https://knowledge.illumina.com/instrumentation/iseq-100/instrumentation-iseq-100-troubleshooting-list/000002611.md).

# Blank BaseSpace login screen during run setup in control software on the iSeq 100

**Background**

This issue only impacts users who are trying to send run data to BaseSpace Sequence Hub for Run Monitoring and Storage or the Proactive Portal (a.k.a. Instrument Health and Data).

During run setup, the typical BaseSpace login screen within the control software may present as a completely blank screen.

**Possible Causes**

* Time or time zone on instrument is incorrect.
* Ports for BaseSpace are being blocked.
* Universal Copy Service (UCS), which is responsible for copying local data to output locations, may not be running.

**Resolutions**

* Update time to the correct internet time.
  * Search 'Time' in Windows and select **Change the data and time**.\
    ![](/files/FfxQ2REAgjDdoDE7GL3U)
  * Toggle 'Set time automatically' and 'Set time zone automatically' and confirm the time is correct.\
    ![](/files/QklUqirMxPOOKycfvwbK)
* If time difference is large, it may be necessary to regenerate Local Run Manager (LRM) certificate.
  * Launch Local Run Manager via HTTPS.
  * From the dashboard navigation bar, select the Tools drop-down list, and then select **System Settings**.
  * Select the Certificates tab.
  * Select **Regenerate the Certificate**.
  * Restart the browser.
  * For more information, see [Local Run Manager v4 product documentation](https://support-docs.illumina.com/SW/lrm_v4/Content/SW/LRM/LRM_v3/SystemCertificates_swLRM.htm).
* Confirm with local IT team that all ports and domains required for BaseSpace are on the allowed list. The required URLs are available [here](https://support.illumina.com/content/dam/illumina-support/documents/product-security/documentation-section/regional-instrument-endpoints/200070476_00_Regional_and_Instrument_Specific_Network_Endpoints_for_Illumina_Cloud_Services.pdf).
* Check if UCS is running (via Task Manager).
  * If UCS is not running, close the control software.
  * In Task Manager, right click on UCS and **Start** the service.
  * Open the control software and restart run set up.

If still unable to login into BaseSpace and the issue requires further troubleshooting, set up the run to be local as a bypass for the BaseSpace Login.

* In the control software, select the hamburger Menu > **System Settings**.
* Under Run Mode, select **None** for BaseSpace Sequence Hub Settings.

  ![](/files/ZFclRgjuKUC09MfLEKSr)

Once the run completes, contact [Illumina Technical Support](https://www.illumina.com/company/contact-us.html#/united-states/technical-support) (<techsupport@illumina.com>) for additional assistance.

\
\
\ <br>

|                                                                                                                                                                                                                                                                                                                                                                        |
| :--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------: |
| *For any feedback or questions regarding this article (Illumina Knowledge Article #2611), contact Illumina Technical Support* [*techsupport@illumina.com*](mailto:techsupport@illumina.com?subject=Question%2FFeedback%20Regarding%20Illumina%20Knowledge%20Article%20#000002611%20-%20Instrumentation%20\&body=Dear%20Illumina%20Technical%20Support,%0D%0A%0D%0A)*.* |


---

# Agent Instructions
This documentation is published with GitBook. GitBook is the documentation platform designed so that both humans and AI agents can read, navigate, and reason over technical content effectively. Learn more at gitbook.com.

## Querying This Documentation
If you need additional information that is not directly available in this page, you can query the documentation dynamically by asking a question.

Perform an HTTP GET request on the current page URL with the `ask` query parameter, and the optional `goal` query parameter:

```
GET https://knowledge.illumina.com/instrumentation/iseq-100/instrumentation-iseq-100-troubleshooting-list/000002611.md?ask=<question>&goal=<endgoal>
```

`ask` is the immediate question: it should be specific, self-contained, and written in natural language.
`goal` is optional and describes the broader end goal you are ultimately trying to accomplish on behalf of the user. GitBook uses it to tailor the answer towards what is most useful for that goal.

The response will contain a direct answer to the question and relevant excerpts and sources from the documentation.

Use this mechanism when the answer is not explicitly present in the current page, you need clarification or additional context, or you want to retrieve related documentation sections.