# How to set up a run on the NextSeq 500/550 Video

This video goes through the necessary steps to take when setting up a run on the Nextseq 500/550.

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{% embed url="<https://www.youtube.com/watch?v=REXkZFtdnDI&ab_channel=Illumina>" %}

Video length: 3:57 min

For further information, see [NextSeq 500 and NextSeq 550 Sequencing System Guide](https://support.illumina.com/downloads/nextseq-500-550-systems-product-documentation.html)

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