# End of Life (EOL) Sale and Support of the MiSeq RUO, MiniSeq and iSeq 100 Systems and Consumables

**Background**

Illumina announced the end of life (EOL) that includes the sale and support for the MiSeq RUO system, certified pre-owned MiSeq RUO system, MiniSeq system, iSeq 100 system, and associated consumables in a Product Obsolescence Notification (PON) sent to customers on **27-MAR-2025**.

This PON was distributed to North, Central, and South America, Europe, Africa, Middle East, and parts of Asia.

**Key Dates**

EOL Announcement: **27-MAR-2025**

Instrument End of Sale (EOS): **30-SEP-2025**

Consumable EOS: **2H 2029 (second half of the year; specific date to be determined in 2029)**

Final EOL: **31-DEC-2029**

**Important Dates about Service Contracts**

New or lapsed Service Contracts **must** be renewed by EOS on **30-SEP-2025**.

* * Instruments that are OFF contract after this date will NOT be eligible for renewal.
  * If a Service Contract is not renewed each year between EOS on **30-SEP-2025** and EOL on **31-DEC-2029**, the user will NOT be able to purchase a new Service Contract.
  * Service Contracts renewed AFTER **31-DEC-2028** will still end **31-DEC-2029**, with Service Contracts being prorated for shortened service period.

For questions about service contracts, see the [Instrument Service Plans](https://www.illumina.com/services/instrument-services/service-plans.html) page.

**Note about replacement parts**, **hardware**, **and consumables**

Illumina will provide a best effort to provide spare or replacement parts for hardware until **31-DEC-2029**, though Illumina cannot guarantee availability or lead times for parts or Advanced Exchange units.

* Certain reagent kits may be discontinued earlier than the second half of 2029 if demand remains low.

Contact [Technical Support](https://www.illumina.com/company/contact-us.html#/united-states/technical-support) to request the full Product Obsolescence Notification and FAQs.

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| *For any feedback or questions regarding this article (Illumina Knowledge Article #9536), contact Illumina Technical Support* [*techsupport@illumina.com*](mailto:techsupport@illumina.com?subject=Question%2FFeedback%20Regarding%20Illumina%20Knowledge%20Article%20#000009536%20-%20Instrumentation%20\&body=Dear%20Illumina%20Technical%20Support,%0D%0A%0D%0A)*.* |


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