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How to clear hard drive space on the NovaSeq X/X Plus

When there is insufficient data storage space on the Compute Engine (CE) drive, a warning notification during the pre-run check will occur.
Delete a Run Only delete runs using the NovaSeq X Series Control Software (rather than manually through the operating systems). Deleting runs manually can negatively impact the control software. A deleted run cannot be requeued. Prior to deleting runs from the NovaSeq X Series Control Software, make sure the runs are backed up on a network drive or in BaseSpace Sequence Hub.
  1. 1.
    Select the instrument icon to open the global navigation menu.
  2. 2.
    Select Settings, and then select Runs.
  3. 3.
    For the run to delete, select the ellipsis icon in the Action column.
  4. 4.
    Select one of the following options:
  • Delete run data—Deletes the sequencing and analysis output folders, but does not remove the run from the Completed tab. The run details will still be available in the control software, but the DRAGEN secondary analysis report is removed.
  • Delete run—Deletes the run data and removes the run from the Completed tab.
  1. 5.
    In the dialog box, confirm run deletion.
  2. 6.
    Repeat steps 3 - 5 to delete runs as needed.
Remove Resources Use the following instructions to remove reference genomes or reference files.
  1. 1.
    Select the instrument icon to open the global navigation menu.
  2. 2.
    Select Settings, and then select Resources.
  3. 3.
    Select the Genomes tab or Reference files tab.
  4. 4.
    For the genome or reference file to remove, select the delete icon.
  5. 5.
    In the dialog box, select Yes, remove to confirm.
  6. 6.
    Repeat steps 4 and 5 for each genome or reference file to remove.
If needed, users can check the CE disk space prior to setting up a run.
Check Disk Space
  1. 1.
    Select the instrument icon to open the global navigation menu.
  2. 2.
    Select Settings, and then select Runs.
  3. 3.
    The available disk space and the disk space used by runs is in the upper right-hand area.
For any feedback or questions regarding this article (Illumina Knowledge Article #7797), contact Illumina Technical Support [email protected].
Last modified 25d ago
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