# End of Life Schedule for NextSeq 1000/2000 SBS Standard Consumables

In effort to streamline Illumina's portfolio and ensure the highest quality products, Illumina obsolesced the following NextSeq 1000/2000 standard SBS reagent kits on December 12, 2025:

* NextSeq 1000/2000 P1 Reagents (100 Cycles)
* NextSeq 1000/2000 P1 Reagents (300 Cycles)\*
* NextSeq 1000/2000 P1 Reagents (600 Cycles)\*
* NextSeq 1000/2000 P2 Reagents (100 Cycles)\*
* NextSeq 1000/2000 P2 Reagents (200 Cycles)\*
* NextSeq 1000/2000 P2 Reagents (300 Cycles)\*
* NextSeq 1000/2000 P2 Reagents (600 Cycles)
* NextSeq 2000 P3 Reagents (50 Cycles)
* NextSeq 2000 P3 Reagents (100 Cycles)\*
* NextSeq 2000 P3 Reagents (200 Cycles)
* NextSeq 2000 P3 Reagents (300 Cycles)\*
* NextSeq 1000/2000 Read and Index Primers
* NextSeq 1000/2000 Index Primer Kit
* NextSeq 1000/2000 Read Primer Kit

On June 3, 2024, Illumina introduced the NextSeq 1000/2000 XLEAP-SBS Reagent Kits to replace the standard SBS kits. Existing customers were notified of this future availability in February 2024 via CCN2024-1513. NextSeq 1000/2000 standard SBS Reagent Kits will continue to be delivered with a guaranteed six-month shelf life up until the obsolescence date December 12, 2025 (\*selected kits have extended availability with last order date pending and dependant on product availability). Available XLEAP reagents are available for purchase on Illumina's website [here](https://www.illumina.com/products/by-type/sequencing-kits/cluster-gen-sequencing-reagents/nextseq-1000-2000-reagents.html/).

A concordance tech note comparing standard SBS and XLEAP SBS datasets on NextSeq 1000/2000 instruments can be found [here](https://www.illumina.com/content/dam/illumina/gcs/assembled-assets/marketing-literature/nextseq-1000-2000-xleap-sbs-tech-note-m-gl-02330/nextseq-1000-2000-xleap-sbs-tech-note-m-gl-02330.pdf).

The XLEAP-SBS Chemistry Quickstart guide, highlighting workflow changes can be found [here](https://support-docs.illumina.com/IN/NextSeq10002000/Content/IN/NextSeq2000_1000/XLEAP_Overview.htm)

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| *For any feedback or questions regarding this article (Illumina Knowledge Article #9213), contact Illumina Technical Support* [*techsupport@illumina.com*](mailto:techsupport@illumina.com?subject=Question%2FFeedback%20Regarding%20Illumina%20Knowledge%20Article%20#000009213%20-%20Instrumentation%20\&body=Dear%20Illumina%20Technical%20Support,%0D%0A%0D%0A)*.* |


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