# How to Enable/Disable Illumina Proactive on the MiSeq

Enable Illumina Proactive on the MiSeq. By connecting MiSeq instrument to Illumina Proactive, Illumina will be alerted to failure risks before they affect a run. Illumina's Service and Support team analyzes instrument performance data, troubleshoots as needed, and schedules any required maintenance.

See below how to enable Illumina Proactive on the MiSeq Software:

**MiSeq Control Software (MCS) v3.1 or below:**

1. From the Home Screen, select Run Options.

![](https://761066130-files.gitbook.io/~/files/v0/b/gitbook-x-prod.appspot.com/o/spaces%2FGM9W2DuBTgEXv1ClCm8H%2Fuploads%2Fgit-blob-be7cc710c81636b0bcb79ddf7175162068684092%2Fimage1.png?alt=media\&token=7bb4d3c1-41ed-4c88-8b9e-25fc979da03b)

2. Select **Send Instrument Performance Data** to Illumina from the Run Settings tab (in some MCS versions, the option may be located in the BaseSpace Settings tab).

![](https://761066130-files.gitbook.io/~/files/v0/b/gitbook-x-prod.appspot.com/o/spaces%2FGM9W2DuBTgEXv1ClCm8H%2Fuploads%2Fgit-blob-cc7a84cde7ec44e2a5b3f3f2d97cdeff6b3b4295%2Fimage2.png?alt=media\&token=e1558243-4df8-478f-9560-d71a07f40359)

**Note**: To monitor the chiller temperature through Illumina Proactive, MiSeq Control Software 3.1 or greater must be installed.

To disable ProActive, de-select **Send Instrument Performance Data to Illumina** in the same tab.

**MiSeq Control Software v4.0 or above:**

1. From the Home Screen, select **System Settings**.

![](https://761066130-files.gitbook.io/~/files/v0/b/gitbook-x-prod.appspot.com/o/spaces%2FGM9W2DuBTgEXv1ClCm8H%2Fuploads%2Fgit-blob-9ebac79aa9b01b539fe66fbbd83995cdfb4cd5b6%2Fimage3.png?alt=media)

2. Under the BaseSpace tab, enable the option **Turn on Illumina Proactive Support**.

![](https://761066130-files.gitbook.io/~/files/v0/b/gitbook-x-prod.appspot.com/o/spaces%2FGM9W2DuBTgEXv1ClCm8H%2Fuploads%2Fgit-blob-1e210d74c0a5317ea32c4bc21fb31e949fcfdd40%2Fimage4.png?alt=media)

To disable ProActive, de-select **Turn on Illumina ProActive Support** in the same tab.

**Additional Resources:**

[Illumina Proactive Webpage](https://www.illumina.com/services/instrument-services-training/product-support-services/instrument-monitoring.html)\
[Illumina Proactive Frequently Asked Questions](https://www.illumina.com/content/dam/illumina-marketing/documents/products/other/illumina-proactive-faq-c-970-2019-004.pdf)\
[Illumina Product Security Portal](https://support.illumina.com/product-security-portal.html)\
\
\
\ <br>

|                                                                                                                                                                                                                                                                                                                                                                        |
| :--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------: |
| *For any feedback or questions regarding this article (Illumina Knowledge Article #2412), contact Illumina Technical Support* [*techsupport@illumina.com*](mailto:techsupport@illumina.com?subject=Question%2FFeedback%20Regarding%20Illumina%20Knowledge%20Article%20#000002412%20-%20Instrumentation%20\&body=Dear%20Illumina%20Technical%20Support,%0D%0A%0D%0A)*.* |