# How to Enable/Disable Illumina Proactive on the MiSeq

Enable Illumina Proactive on the MiSeq. By connecting MiSeq instrument to Illumina Proactive, Illumina will be alerted to failure risks before they affect a run. Illumina's Service and Support team analyzes instrument performance data, troubleshoots as needed, and schedules any required maintenance.

See below how to enable Illumina Proactive on the MiSeq Software:

**MiSeq Control Software (MCS) v3.1 or below:**

1. From the Home Screen, select Run Options.

![](/files/HmmWDtKsXKufVTH8gOaV)

2. Select **Send Instrument Performance Data** to Illumina from the Run Settings tab (in some MCS versions, the option may be located in the BaseSpace Settings tab).

![](/files/viHkNtzrp7cMq41lUlBL)

**Note**: To monitor the chiller temperature through Illumina Proactive, MiSeq Control Software 3.1 or greater must be installed.

To disable ProActive, de-select **Send Instrument Performance Data to Illumina** in the same tab.

**MiSeq Control Software v4.0 or above:**

1. From the Home Screen, select **System Settings**.

![](/files/NCkYx1GjOBaGUwJmHjCn)

2. Under the BaseSpace tab, enable the option **Turn on Illumina Proactive Support**.

![](/files/x5GBAx5Pa9WJr8Uw5R6r)

To disable ProActive, de-select **Turn on Illumina ProActive Support** in the same tab.

**Additional Resources:**

[Illumina Proactive Webpage](https://www.illumina.com/services/instrument-services-training/product-support-services/instrument-monitoring.html)\
[Illumina Proactive Frequently Asked Questions](https://www.illumina.com/content/dam/illumina-marketing/documents/products/other/illumina-proactive-faq-c-970-2019-004.pdf)\
[Illumina Product Security Portal](https://support.illumina.com/product-security-portal.html)\
\
\
\ <br>

|                                                                                                                                                                                                                                                                                                                                                                        |
| :--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------: |
| *For any feedback or questions regarding this article (Illumina Knowledge Article #2412), contact Illumina Technical Support* [*techsupport@illumina.com*](mailto:techsupport@illumina.com?subject=Question%2FFeedback%20Regarding%20Illumina%20Knowledge%20Article%20#000002412%20-%20Instrumentation%20\&body=Dear%20Illumina%20Technical%20Support,%0D%0A%0D%0A)*.* |


---

# Agent Instructions: Querying This Documentation

If you need additional information that is not directly available in this page, you can query the documentation dynamically by asking a question.

Perform an HTTP GET request on the current page URL with the `ask` query parameter:

```
GET https://knowledge.illumina.com/instrumentation/miseq/instrumentation-miseq-reference_material-list/000002412.md?ask=<question>
```

The question should be specific, self-contained, and written in natural language.
The response will contain a direct answer to the question and relevant excerpts and sources from the documentation.

Use this mechanism when the answer is not explicitly present in the current page, you need clarification or additional context, or you want to retrieve related documentation sections.