Which BaseSpace apps and features use Illumina BioInsight Platform Core

Illumina BioInsight Platform Core (Platform Core, formerly, Illumina Connected Analytics (ICA)) is a cloud-based software platform intended to be used to manage, analyze, and interpret large volumes of multiomics data in a secure, scalable, and flexible environment. With BaseSpace utilizing underlying features in Platform Core, it allows BaseSpace users to take advantage of the features and technology in Platform Core.

BaseSpace Apps

The following BaseSpace Apps currently perform analysis in Illumina BioInsight Platform Core

• BCL Convert

• BaseSpace to ICA Data Copy

• All latest versions of DRAGEN applications with the following exceptions:

  • DRAGEN Metagenomics Pipeline v3.7.0

  • DRAGEN PopGen v4.3.6

  • DRAGEN Differential Expression v4.4.4000

  • Dragen Joint Genotyping Pipeline v4.4.6000

  • DRAGEN FastQC + MultiQC v3.9.5001

Sequencing Runs

The following sequencing runs use Platform Core, but all files and features are accessible through BaseSpace.

• The NovaSeq X Series and MiSeq i100 systems will connect through BaseSpace and ultimately store the run files in Platform Core. During login, the NovaSeq X Control software will verify that all BaseSpace and Platform Core resources are available to make sure no issues occur during run upload.

• The NextSeq 1000/2000 will upload sequencing run files directly to BaseSpace. Starting with BCL Convert or DRAGEN 4.2.7 Planned Run Analysis, the FASTQ files and all other downstream analysis files will be stored in Platform Core.

Run Planning

All cloud analyses setup in BaseSpace Run Planning will use Platform Core to perform the secondary analysis, including autolaunch analyses.

BaseSpace Resources

When uploading resources through the Resources Tab, the files will be uploaded to Platform Core so they are accessible for any DRAGEN analysis. This includes BED files and custom reference hash tables.

BaseSpace Transfers

Any runs or projects containing data in Platform Core may take up to 24 hours to complete transfer. When the transfer is accepted, the items will be immediately visible in the recipients account, but downloading the data or using it as input will be restricted until the transfer process has completed.

Data Archive

Archiving any data that is based in Platform Core cannot currently be archived in BaseSpace. This feature will be enabled in a future BaseSpace release.

For any feedback or questions regarding this article (Illumina Knowledge Article #9045), contact Illumina Technical Support [e-mail].