How to perform the Factory Restore on the MiSeq i100 Series

Background

The Factory Restore option allows Administrator users to restore the instrument to the default factory settings if there is an irrecoverable error on the MiSeq i100 Series instrument.

Important Information

The Factory Restore option PERMANENTLY ERASES all data on the instrument including Sequencing Run data, and should only be performed at the explicit recommendation of Illumina Technical or Field Support teams. The DRAGEN BCL Convert application is the only Application that is retained on Factory Restore, all other DRAGEN Applications must be re-installed after completing the Factory Restore and First Time Setup.

The Factory Restore process takes about 90 minutes and it cannot be canceled after it is initiated.

Resolution Actions

If the Factory Restore option is recommended by either Illumina Technical Support or Field Support teams, see the following steps to complete the process:

1. Login to the MiSeq i100 Series Control Software using a local Administrator account.

2. Select the menu icon in the top-left corner, then select Settings.

3. Select Factory Restore.

4. Review the information presented on the Factory Restore page, and select Restore to proceed.

5. Once complete, the instrument will restart to complete the process. Do NOT power cycle or restart the instrument during the Factory Restore process.

6. Once the Control Software has initialized, complete First Time Setup.

   1. Refer to theFirst Time Setupsection in the MiSeq i100 Series Product Documentation for details.

7. If additional DRAGEN Applications are required, download and re-install desired DRAGEN Applications and associated Reference Genomes.

   1. Refer to the Applications section in the MiSeq i100 Series Product Documentation for details.

8. Re-install the DRAGEN License files:

   1. Online Installation

      1. Login to the MiSeq i100 Series Control Software using a local Administrator account.

      2. Select the menu icon in the top-left corner, then select Settings.

      3. Select DRAGEN, then select the License tab.

      4. Select Update from license server.

      5. Once installation is complete, confirm that the Valid Until and Serial Number fields have populated.

   2. Offline Installation

      1. See Knowledge Article Offline DRAGEN License Installation on the MiSeq i100 Series for details.

If there are any issues during the Factory Restore, First Time Setup, or DRAGEN License and Application installation process, contact Illumina Technical Support.

For any feedback or questions regarding this article (Illumina Knowledge Article #10158), contact Illumina Technical Support [e-mail].