# Air Filter replacement on the MiSeq i100

The air filter is single use and covers the fan in the back of the instrument. It ensures proper cooling and prevents debris from entering the system. The instrument is shipped with one air filter installed and one spare. Additional air filters are included with an active instrument service contract (filters are not sent automatically; rather, users can request them by sending an email to Illumina Technical Support, <techsupport@illumina.com>), or they can be purchased separately from Illumina.

MiSeq i100 Air Filter catalog number: **20116201**

Use the following instructions to replace an expired air filter every 6 months.

**Replace Air Filter**

1. Position the instrument to easily access the back of it.
2. On the back of the instrument, pull the top edge of the rear panel away from the instrument to access the air filter.

![](/files/74g62oGPaPWWIw8qgSQv)

3. Remove and discard the used air filter.
4. Insert the new air filter into the tray. Ensure the filter is inserted so that the filter tab faces outward and sits against the rear panel.

![](/files/FIShdgP1WVZX5RgK4rdi)

5. Close the rear panel.
6. Select **Reset filter expiry**.
7. Return the instrument to its original placement.

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| *For any feedback or questions regarding this article (Illumina Knowledge Article #9998), contact Illumina Technical Support* [*techsupport@illumina.com*](mailto:techsupport@illumina.com?subject=Question%2FFeedback%20Regarding%20Illumina%20Knowledge%20Article%20#000009998%20-%20Instrumentation%20\&body=Dear%20Illumina%20Technical%20Support,%0D%0A%0D%0A)*.* |


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