> For the complete documentation index, see [llms.txt](https://knowledge.illumina.com/llms.txt). Markdown versions of documentation pages are available by appending `.md` to page URLs; this page is available as [Markdown](https://knowledge.illumina.com/instrumentation/miniseq/instrumentation-miniseq-reference_material-list/000002295.md).

# Installing and using Local Run Manager Modules on the iSeq 100

**Background**

Local Run Manager (LRM) uses modules for performing Secondary Analysis on the iSeq 100. Modules must be installed before setting up any sequencing runs with on-instrument Secondary Analysis through LRM. See the following instructions for installing and using the LRM Modules.

**Installing Local Run Manager (LRM) Modules on the iSeq 100**

1. Switch to the `sbsadmin` Windows operating system (OS) account.
2. Download the software installer(s) from the [Local Run Manager support pages](https://support.illumina.com/sequencing/sequencing_software/local-run-manager/downloads.html). Save the installer(s) to a network location or portable USB drive.
3. Copy the installer(s) to `C:\Illumina`
4. Open the installer (\*.exe), and then follow the prompts to perform the install. If User Management is turned off in LRM, select **Next** when prompted for LRM Credentials. If User Management is enabled, enter LRM Administrator credentials.
5. When the update is complete, select **Finish**.

**How to access LRM after the module installation**

1. Open Chrome or Chromium program.
2. Type in `localhost` into the address bar, then press **Enter**.
3. If prompted, log in using LRM account credentials.
   1. Contact [Illumina Technical Support](https://www.illumina.com/company/contact-us.html#/united-states/technical-support) for assistance setting up LRM user accounts.
4. If newly installed modules do not appear, force refresh the browser by holding `Ctrl+Shift+R`.

For the previous runs with manual setup or the runs which need reanalysis, follow the instructions in Knowledge Article [How to requeue and import run data for reanalysis with Local Run Manager](/instrumentation/general/instrumentation-general-reference_material-list/000001324.md) to perform reanalysis.

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| *For any feedback or questions regarding this article (Illumina Knowledge Article #2295), contact Illumina Technical Support* [*techsupport@illumina.com*](mailto:techsupport@illumina.com?subject=Question%2FFeedback%20Regarding%20Illumina%20Knowledge%20Article%20#000002295%20-%20Instrumentation%20\&body=Dear%20Illumina%20Technical%20Support,%0D%0A%0D%0A)*.* |


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