> For the complete documentation index, see [llms.txt](https://knowledge.illumina.com/llms.txt). Markdown versions of documentation pages are available by appending `.md` to page URLs; this page is available as [Markdown](https://knowledge.illumina.com/instrumentation/iseq-100/instrumentation-iseq-100-troubleshooting-list/000002264.md).

# iSeq 100 unable to connect to BaseSpace due to Proxy server issues

#### Phenotype

Universal Copy Service can have issues navigating a user's Proxy systems. This manifests as Basepace not connecting (BaseSpace Hosting locations missing in the software settings or other connectivity or upload issues).

![](/files/vXJdhN6sWtHQ1HGA9254)

#### Resolution

Follow the instructions below from the system guide on how to *Connect to a Proxy Server*. These instructions should be done only with a user's IT representative or system administrator:

1. Minimize the control software.
2. From Windows Start, open the Run dialog box.
3. Enter `cmd`, and then select **OK**.
4. Enter the following command:\
   C:\windows\System32\bitsadmin.exe /Util /SetIEProxy LocalSystem Manual\_proxy http\://: NULL
5. Replace http\://: with your proxy server address and proxy port and `NULL` with any bypasses.
6. Press **Enter** to run the command.
7. Power cycle the instrument. See [Power cycling the iSeq 100](/instrumentation/iseq-100/instrumentation-iseq-100-reference_material-list/000002289.md).

Reference information in iSeq 100 Sequencing System support documentation: [Network Setup](https://support-docs.illumina.com/IN/iSeq100/Content/IN/iSeq/NetworkSetup_fISQ.htm?Highlight=proxy%20server).

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| *For any feedback or questions regarding this article (Illumina Knowledge Article #2264), contact Illumina Technical Support* [*techsupport@illumina.com*](mailto:techsupport@illumina.com?subject=Question%2FFeedback%20Regarding%20Illumina%20Knowledge%20Article%20#000002289%20-%20Instrumentation%20\&body=Dear%20Illumina%20Technical%20Support,%0D%0A%0D%0A)*.* |


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