> For the complete documentation index, see [llms.txt](https://knowledge.illumina.com/llms.txt). Markdown versions of documentation pages are available by appending `.md` to page URLs; this page is available as [Markdown](https://knowledge.illumina.com/instrumentation/general/instrumentation-general-reference_material-list/000010233.md).
# Installing Reference Genomes on NovaSeq X Series Control Software v1.4
**Background**
Certain DRAGEN Secondary Analysis workflows utilize reference Genomes for alignment and variant calling. These workflows require that the Genomes are installed onto the instrument so they are accessible by the DRAGEN Secondary Analysis.
Due to the file size of the Genomes and disk space limitations on the NovaSeq X Series instrument, users are not able to install all available Genomes on the instrument. The following Table lists available packaged and individual Genomes, as well as the file sizes for each Genome.
For installation instructions, see the [Software Updates](https://support-docs.illumina.com/IN/NovaSeqX/Content/SoftwareUpdates.htm) section of the NovaSeq X Series Product documentation.
**Table 1**. Available packaged and individual reference v11 Genomes with disk space requirements for each.
**Table 2**: Available packaged and individual reference v10 Genomes with disk space requirements for each.
For an interactive reference Genomes checklist and disk space estimator, contact [Illumina Technical Support](https://www.illumina.com/company/contact-us.html#/united-states/technical-support).
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| *For any feedback or questions regarding this article (Illumina Knowledge Article #10233), contact Illumina Technical Support* [*techsupport@illumina.com*](mailto:techsupport@illumina.com?subject=Question%2FFeedback%20Regarding%20Illumina%20Knowledge%20Article%20#000010233%20-%20Instrumentation%20\&body=Dear%20Illumina%20Technical%20Support,%0D%0A%0D%0A)*.* |
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