> For the complete documentation index, see [llms.txt](https://knowledge.illumina.com/llms.txt). Markdown versions of documentation pages are available by appending `.md` to page URLs; this page is available as [Markdown](https://knowledge.illumina.com/instrumentation/general/instrumentation-general-reference_material-list/000009316.md).

# Introducing the Illumina NovaSeq X System

**Background**

Coinciding with the v1.3 NovaSeq X Control Software release, Illumina is launching the NovaSeq X Sequencing System, a single-sided version of the NovaSeq X Series platform.

**Important Notes for the NovaSeq X Sequencing System:**

* The instrument can sequence all available NovaSeq X Series Kit configurations.
* The instrument will be single-sided and will only allow sequencing on Side A of the instrument.

  ![](https://761066130-files.gitbook.io/~/files/v0/b/gitbook-x-prod.appspot.com/o/spaces%2FGM9W2DuBTgEXv1ClCm8H%2Fuploads%2Fgit-blob-f65b1c8316f90e29fd1a1015f8d5c04d67213c69%2Fimage1.png?alt=media)
* The NovaSeq X instrument is fully upgradeable to a NovaSeq X Plus instrument. The upgrade is performed by an Illumina Field Service Engineer (FSE) only. Contact your local Sales team for further information.

  ![](https://761066130-files.gitbook.io/~/files/v0/b/gitbook-x-prod.appspot.com/o/spaces%2FGM9W2DuBTgEXv1ClCm8H%2Fuploads%2Fgit-blob-4a8fef0d53e63d72754ecfd1b183fa19d919fcf7%2Fimage2.png?alt=media)

**Maintenance Notes for the NovaSeq X Instrument:**

* The System Check within the Control Software are programed to test side A only.
* The NovaSeq X instrument comes with 1 wash flow cell and 1 wash cartridge set to allow Side A maintenance washes.
* The Control Software allows the user to open the front doors for Sides A and B for the Air Filter replacement by clicking "Unlock doors" option in the Control Software > Settings.

  ![](https://761066130-files.gitbook.io/~/files/v0/b/gitbook-x-prod.appspot.com/o/spaces%2FGM9W2DuBTgEXv1ClCm8H%2Fuploads%2Fgit-blob-4adf49f98a1ec2ff7bbe7c1a14d37473151ce5d3%2Fimage3.png?alt=media)

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| *For any feedback or questions regarding this article (Illumina Knowledge Article #9316), contact Illumina Technical Support* [*techsupport@illumina.com*](mailto:techsupport@illumina.com?subject=Question%2FFeedback%20Regarding%20Illumina%20Knowledge%20Article%20#000009316%20-%20Instrumentation%20\&body=Dear%20Illumina%20Technical%20Support,%0D%0A%0D%0A)*.* |


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